Glycine has an isoelectric point of $6.2$. Define isoelectric point.
Draw the structure of glycine at $\text{pH }4$.
Fig. 6.1 illustrates two syntheses that begin with glycine.
State the necessary conditions for reaction 1.
Identify the reagent used in reaction 2.
Draw the structure of the organic product $U$ formed when hippuric acid reacts with an excess of $\text{LiAlH}_4$ in reaction 3.
One molecule of phenylalanine, $R$, may react with one molecule of glycine to produce two dipeptides, $S$ and $T$. $S$ and $T$ are structural isomers. Draw the structures of these dipeptides. The peptide bond formed should be shown fully displayed.
Explain why amides are weaker bases than amines.
The $\text{p}K_a$ of chloroethanoic acid is $2.86$ whereas the $\text{p}K_a$ of ethanoic acid is $4.76$. Explain the difference between these two $\text{p}K_a$ values.
Complete Table 6.2 for the proton ($^1\text{H}$) NMR spectrum of $V$ recorded in $\text{CDCl}_3$. Table 6.1 provides some relevant data.
Complete Table 6.3 by placing a tick ($\checkmark$) to show any protons whose peaks are still seen in the proton ($^1\text{H}$) NMR spectrum of $V$ recorded in $\text{D}_2\text{O}$.
Complete Table 6.2 for the proton ($^1\text{H}$) NMR spectrum of $V$ recorded in $\text{CDCl}_3$. Table 6.1 provides some relevant data.
Complete Table 6.3 by placing a tick ($\checkmark$) to show any protons whose peaks are still seen in the proton ($^1\text{H}$) NMR spectrum of V recorded in $\text{D}_2\text{O}$.