Sickle-cell anaemia is an inherited disorder. Fig. 5.1 shows a photomicrograph of some blood cells taken from a person with sickle-cell anaemia. The diagram identifies a red blood cell with a sickle shape.
(a)[3]
Explain how red blood cells develop a sickle shape.
(b)[4]
Explain how sickle-cell anaemia is inherited by affected people.
(c(i))[2]
Define the term species in biology.
(c(ii))[5]
Explain how the sickle-cell allele is distributed in human populations.
Worked solution & mark scheme
This 14-mark question has a full step-by-step worked solution and mark scheme. One marking point: “mutation brings about a change in the DNA/base sequence” …