Biology 0610 · IGCSE · Chromosomes, genes and proteins

Chromosomes, genes and proteins — practice question

Sickle-cell anaemia results from a mutation in the haemoglobin gene. The normal base sequence is given in 1, while the sickle-cell base sequence is given in 2. 1 TGA GGA CTC CTC 2 TGA GGA CAC CTC What is responsible for the alteration in the DNA?

  • Athe addition of one base
  • Bthe addition of two bases
  • Cthe change of one base for another
  • Dthe deletion of one base

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