Chemistry 9701 · AS & A Level · States of matter

States of matter — practice question

Most everyday drugs are swallowed, although some medicines, for example protein-based ones, are given by injection so that they are not decomposed in the digestive system.
(a(i))[1]

Name a functional group found in drug molecules that could be broken down by acid in the stomach.

(a(ii))[1]

State the type of reaction that would lead to such a breakdown.

(a(iii))[2]

Which one of the following compounds would not be suitable to be taken orally?

(a(iv))[5]

On the structure of your chosen compound in (iii), circle all the functional groups that might be broken down by acid.

(b(i))[2]

State and explain in which location, $P$, $Q$ or $R$, a hydrophobic drug could be carried.

(b(ii))[2]

By considering the nature of the functional groups in $A$, $B$ and $C$, explain why these drugs can be carried at position $R$ in the liposome.

(c(i))[1]

Suggest the size of the nano-cages in metres.

(c(ii))[2]

Suggest why infra-red, rather than higher frequency radiation is used.

Worked solution & mark scheme

This 16-mark question has a full step-by-step worked solution and mark scheme. One marking point: Amide or ester or peptide group identified

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