Chemistry 9701 · AS & A Level · States of matter

States of matter — practice question

Noradrenaline is both a hormone and a neurotransmitter, and it is released when the body is under stress to make the heart beat faster and raise blood pressure.
(a)[3]

State the names of three functional groups in the noradrenaline molecule.

(b(i))

Look at the two-step synthesis of noradrenaline from dihydroxybenzaldehyde below. Draw the structure of the intermediate $Z$ and suggest reagents for steps 1 and 2.

(b(ii))[5]

Dihydroxybenzaldehyde reacts with $\text{Br}_2\text{(aq)}$. Describe what can be seen in this reaction. Draw the structure of the product.

(c(i))

Draw the structures of the products when noradrenaline is reacted with dilute $\text{NaOH(aq)}$.

(c(ii))

Draw the structures of the products when noradrenaline is reacted with dilute $\text{HCl(aq)}$.

(c(iii))[4]

Draw the structures of the products when noradrenaline is reacted with an excess of ethanoyl chloride, $\text{CH}_3\text{COCl}$.

(d)[2]

Name the new functional groups formed in the reaction in (c)(iii).

Worked solution & mark scheme

This 14-mark question has a full step-by-step worked solution and mark scheme. One marking point: Phenol functional group

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