Chemistry 9701 · AS & A Level · Reaction kinetics

Reaction kinetics — practice question

Enzymes are a distinct class of protein molecules found in large quantities in living organisms. They act as catalysts but, unlike inorganic catalysts, they usually catalyse just one specific reaction.
(a)[2]

Inorganic catalysts often work better when heated, but enzymes seldom function at temperatures much above $45^\circ\text{C}$. Explain why this happens.

(b)[3]

Using the shape below as an enzyme, sketch how an enzyme shows specificity for breaking down one particular substrate molecule.

(c)[2]

Describe the effects of a competitive inhibitor and a non-competitive inhibitor on the interaction between enzyme and substrate.

(d(i))

The diagram below shows an enzyme-catalysed reaction. On the diagram, sketch the graph that would appear if the same reaction were carried out in the presence of a non-competitive inhibitor.

(d(ii))[3]

Explain why a non-competitive inhibitor produces this effect on the reaction.

Worked solution & mark scheme

This 10-mark question has a full step-by-step worked solution and mark scheme. One marking point: Protein structure held together by hydrogen/ionic/van der Waals bonds; these bonds break above $45^\circ \text{C}$

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