Chemistry 9701 · AS & A Level · Polymerisation

Polymerisation — practice question

In the body’s important reactions for growth and repair, amino acids join together to make polymers called proteins.
(a(i))

What kind of reaction is this polymerisation?

(a(ii))[3]

Using the same three-letter abbreviations for the amino acids, and starting from stocks of glycine and alanine, give the structures of every other dipeptide that could be formed from these amino acid stocks. The dipeptide gly-ala is already given.

(b(i))

Draw a DNA section with two base pairs, using blocks to represent the different components. All components should be labelled.

(b(ii))[4]

Suggest the effect on DNA replication if the hydrogen bonds between the strands were replaced by stronger bonds, for example covalent bonds.

(c(i))

Explain why some changes in the triplet code do not cause any change in the primary structure of a protein.

(c(ii))

Suggest what alteration in the tertiary structure of a protein would happen if a mutation replaced aspartic acid with glycine.

(c(iii))[3]

Sometimes a mutation causes the deletion of one base in DNA (or RNA). Explain why this is likely to have more serious effects on the protein than changing one base to another.

Worked solution & mark scheme

This 10-mark question has a full step-by-step worked solution and mark scheme. One marking point: Condensation is the reaction type identified

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