(a(i))[1]
Name the cells that contain haemoglobin.
(a(ii))[1]
From Fig. 4.1, determine the percentage saturation of myoglobin and adult haemoglobin at a partial pressure of oxygen of $3\text{ kPa}$.
(a(iii))[2]
There is a marked gap between the percentage saturation of myoglobin and adult haemoglobin at low partial pressures of oxygen. Suggest reasons for this.
(b(i))[2]
Explain, using Fig. 4.1, why the difference in oxygen-binding affinity between fetal and adult haemoglobin is important.
(b(ii))[1]
Suggest why HPFH usually has no symptoms.
(c)[2]
Sketch on Fig. 4.2 the dissociation curve that would be expected for adult haemoglobin when the concentration of carbon dioxide is increased.