Biology 9700 · AS & A Level · The immune system

The immune system — practice question

Myasthenia gravis is a disorder that causes muscle weakness because it affects the immune response.
(a)[2]

Explain what the term immune response means.

(b(i))[3]

Myasthenia gravis is an autoimmune disease that interferes with a cell signalling pathway involving muscle cells. Suggest how the immune system acts to disrupt this cell signalling pathway.

(b(ii))[4]

Enzyme Y is located in the cell surface membrane of muscle cells. Enzyme Y functions to break down the cell signalling molecules that trigger muscle contraction when they are no longer required. Using the induced fit hypothesis of enzyme action, explain how enzyme Y breaks down the cell signalling molecules.

(c)[3]

Explain the advantages of using monoclonal antibodies in the treatment of diseases such as myasthenia gravis.

Worked solution & mark scheme

This 12-mark question has a full step-by-step worked solution and mark scheme. One marking point: Identifies non-self / foreign antigens

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