Biology 9700 · AS & A Level · The immune system

The immune system — practice question

T-helper lymphocytes and Leydig cells are both mammalian cell types. Their principal function is to make and release cell-signalling molecules. T-helper lymphocytes make proteins called cytokines. Leydig cells make the steroid (lipid) hormone testosterone from cholesterol. Leydig cells also make cholesterol.
(a)[1]

State one way in which cytokines take part in an immune response.

(b(i))[2]

State, with reasons, whether Fig. 3.1 shows part of a Leydig cell or part of a T-helper lymphocyte.

(b(ii))[2]

Underline the correct name for the type of image shown in Fig. 3.1 and justify your choice.

(c(i))[2]

Outline one way in which testosterone molecules could enter their target cells.

(c(ii))[2]

Cytokine molecules are unable to enter their target cells. Suggest and explain why cytokine molecules are unable to cross the cell surface membrane to enter their target cells.

Worked solution & mark scheme

This 9-mark question has a full step-by-step worked solution and mark scheme. One marking point: Any one immune response that is stimulated or suppressed (for example, antibody production, macrophage response, chemotaxis)

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