Biology 9700 · AS & A Level · Testing for biological molecules

Testing for biological molecules — practice question

Stem cells occur all over the human body. Lgr5$^{+}$ stem cells are located in the lining of the small intestine. Fig. 2.1 is a flow chart showing the stages in the development of one daughter cell produced by the mitotic division of an Lgr5$^{+}$ stem cell.
(a(i))[2]

Explain why stem cells are needed in places such as the lining of the small intestine.

(a(ii))[1]

Name the mitosis stage shown in cell X in Fig. 2.1.

(a(iii))[1]

State which part of the cell cycle is shown at Y in Fig. 2.1.

(b)[2]

Explain the function of centromeres in the cell cycle.

(c)[6]

Fig. 2.2 shows three kinds of specialised cell that develop from Lgr5$^+$ stem cells in the small intestine. Suggest a function of each of the cells shown in Fig. 2.2, and explain how the structure of each cell supports your suggestion.

Worked solution & mark scheme

This 12-mark question has a full step-by-step worked solution and mark scheme. One marking point: Stem cells replace damaged or dead cells

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