(a)[2]
Explain why telomeres are important.
(b)[1]
Suggest why telomerase is found in much greater amounts in stem cells and cancer cells than in other cell types.
(c)[1]
Research indicates that telomerase is a flexible molecule when it binds its substrate. Its active site changes shape slightly so the enzyme-substrate complex can form. Name the theory that describes this way of enzyme action.
(d)[2]
An investigation was done into how substrate concentration affects telomerase activity. The findings are shown in Fig. 6.1. Using Fig. 6.1, explain why the reaction rates for telomerase at a substrate concentration of $0.2\,\mu\text{mol dm}^{-3}$ and at $1.6\,\mu\text{mol dm}^{-3}$ differ.