Biology 9700 · AS & A Level · Structure of nucleic acids and replication of DNA

Structure of nucleic acids and replication of DNA — practice question

Extracellular growth factors help regulate the cell cycle in certain mammalian cells. One example is epidermal growth factor (EGF). Fig. 6.1 illustrates the events that take place when EGF is present on the surfaces of two cells, A and B.
(a)[2]

Explain why cell A in Fig. 6.1 responds to EGF, whereas cell B does not.

(b)[1]

More mRNA is made in the $G_1$ phase than in mitosis. Suggest why this is the case.

(c)[3]

DNA is copied during the S phase of the cell cycle. EGF is one of several factors that stimulate the transition from the $G_1$ phase to the S phase. State the substances used to make DNA during the S phase.

(d(i))[2]

Fig. 6.2 shows chromosome 1 from rice, $Oryza\ sativa$, during metaphase of mitosis. State the name and the function of the chromosome region labelled X.

(d(ii))[2]

In the cell outline below, draw the chromosome from Fig. 6.2 as it would look in anaphase of mitosis.

Worked solution & mark scheme

This 10-mark question has a full step-by-step worked solution and mark scheme. One marking point: EGF attaches to a complementary receptor on cell A

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