Fig. 1.1 shows a transmission electron micrograph of a mitochondrion. With reference to Fig. 1.1, complete Table 1.1 by using the letters A-D to indicate where each stage of aerobic respiration takes place. Any letter may be used once, more than once or not at all.
In anaerobic conditions, oxidative phosphorylation cannot make any ATP because it stops. Explain why ATP synthesis by oxidative phosphorylation stops in anaerobic conditions.
As much as $60\%$ of the ATP made in cancer cells is generated by lactate fermentation of glucose, despite oxygen being present. Scientists are developing cancer treatments that inhibit the enzyme responsible for the final step of lactate fermentation. Explain how blocking this enzyme lowers ATP production in cancer cells.