Mutations in either the BRCA1 gene or the BRCA2 gene account for most inherited breast cancer in humans. The proteins made by these two genes move into the nucleus, where they interact with other proteins, including those produced by the tumour suppressor gene p53 and the DNA repair gene RAD51. Which combination of gene activity is most likely to lead to breast cancer?
Biology 9700 · AS & A Level · Replication and division of nuclei and cells