Mutations in either the $\text{BRCA1}$ gene or the $\text{BRCA2}$ gene account for most inherited breast cancer in humans. The proteins made by these two genes move into the nucleus, where they interact with other proteins, including those encoded by the tumour suppressor gene, $\text{p53}$, and the DNA repair gene, $\text{RAD51}$. Which pattern of gene activity is most likely to lead to breast cancer?
- A$\text{BRCA1 or BRCA2}$: ✓, $\text{p53}$: ✓, $\text{RAD51}$: ✓
- B$\text{BRCA1 or BRCA2}$: ✓, $\text{p53}$: ✓, $\text{RAD51}$: \times
- C$\text{BRCA1 or BRCA2}$: ✓, $\text{p53}$: \times, $\text{RAD51}$: ✓
- D$\text{BRCA1 or BRCA2}$: \times, $\text{p53}$: \times, $\text{RAD51}$: \times