The mode of action for four drugs that block DNA replication is given here. Aphidicholine blocks DNA polymerase. Cytarabine is changed into a molecule that can replace a DNA nucleotide and it also blocks DNA repair mechanisms. Epirubicin blocks an enzyme needed for DNA unwinding and strand separation. Hydroxycarbamide blocks an enzyme involved in making deoxyribonucleotides. Which row pairs a drug with the correct explanation of its mechanism of action?
Biology 9700 · AS & A Level · Replication and division of nuclei and cells