Pyruvate carboxylase (PC) deficiency is an uncommon disease. In a person with PC deficiency, the rate of respiration in the cells is much lower than normal. The passage below sets out the occurrence of PC deficiency in human populations. Complete the passage using the most suitable scientific terms. PC deficiency affects one in 250000 people. A person either has the disease or does not, so there are no intermediate forms of the disease. PC deficiency is caused by a genetic mutation in one gene. Whether a person develops the disease is not influenced by ................................ factors. The distribution of PC deficiency in human populations shows ................................ variation.
Outline the functions of named coenzymes in aerobic respiration.