Biology 9700 · AS & A Level · Passage of information from parents to offspring

Passage of information from parents to offspring — practice question

The fruit fly, Drosophila melanogaster, shows many phenotypic variations and has been used in experiments to illustrate the principles of inheritance.
(a)[5]

Most fruit flies have red eyes, although there is a white-eyed variant. Fig. 7.1 presents the red-eyed and white-eyed fruit fly variants. The gene for eye colour is on the X chromosome. Using suitable symbols, draw a genetic diagram to show the possible offspring from a cross between a heterozygous red-eyed female fruit fly and a white-eyed male fruit fly.

(b(i))[1]

One gene involved in blood clotting in humans is also found on the X chromosome. A rare gene variant, a recessive allele for haemophilia, can cause the blood to fail to clot properly. State why a man who has haemophilia cannot pass the condition to his son.

(b(ii))[1]

Queen Victoria of Great Britain in the 19th century was a carrier of haemophilia, but she did not have the condition. State the term used to describe the genotype of a carrier.

(b(iii))[1]

Neither of Queen Victoria’s parents carried the haemophilia allele. Suggest how Queen Victoria might have become a carrier.

Worked solution & mark scheme

This 8-mark question has a full step-by-step worked solution and mark scheme. One marking point: Accurate use of the symbols $X^A$ for red-eye and $X^a$ for white-eye

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