Biology 9700 · AS & A Level · Mode of action of enzymes

Mode of action of enzymes — practice question

Furanocoumarins are compounds present in some fruits, and they inhibit the enzyme CYP3A4. This enzyme is required to break down toxins in the human digestive system, so harmful amounts of these toxins could build up if these fruits are consumed. What does this information indicate about molecules of the enzyme CYP3A4?

  • AThey lower the activation energy of the toxin breakdown process.
  • BThey show specificity for a particular substrate found in fruits.
  • CThey will change permanently when acted upon by furanocoumarin molecules.
  • DThey will resume normal activity when levels of furanocoumarins decrease.

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