Biology 9700 · AS & A Level · Mode of action of enzymes

Mode of action of enzymes — practice question

The figure illustrates sucrose and sucralose. The enzyme sucrase hydrolyses sucrose but is unable to hydrolyse sucralose. Four students were asked to propose reasons why sucrase can hydrolyse sucrose but not sucralose. Three of the students made correct proposals. Which proposal cannot be correct?

  • AThe Cl atoms change the shape of the sucralose molecule so it is not the same shape as the active site of sucrase.
  • BThe Cl atoms of the modified fructose cannot bind to the active site of sucrase.
  • CThe Cl atoms cannot cause an induced fit, so sucralose does not enter the active site of sucrase.
  • DThe Cl atoms cause fewer temporary hydrogen bonds between sucralose and the active site of sucrase.

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