Biology 9700 · AS & A Level · Infectious diseases

Infectious diseases — practice question

When cholera bacteria are in the intestine, they release the toxin cholera­gen.
(a(i))[1]

Name the bacterium responsible for cholera.

(a(ii))[2]

Describe how cholera is passed from an infected person to a person who is not infected.

(b)[2]

Suggest how cholera­gen interacts with gangliosides on intestinal epithelial cells.

(c)[1]

Name the process shown in Fig. 6.1 by which cholera­gen enters the intestinal epithelial cell.

(d)[2]

Suggest and explain the likely effects on the intestinal epithelial cells of chloride ions being lost through the channel proteins.

(e)[3]

Health authorities advise that antibiotics, such as tetracycline, should be used only to treat people with severe cases of cholera. Explain why antibiotics should not be given to people with mild cholera or used to protect people from cholera.

Worked solution & mark scheme

This 11-mark question has a full step-by-step worked solution and mark scheme. One marking point: The answer is $Vibrio\ cholerae$.

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