Biology 9700 · AS & A Level · Gene control

Gene control — practice question

(a)[4]

Penicillin belongs to the antibiotics known as β‑lactams, and all of them act on bacteria in the same way. Describe how penicillin kills non-resistant bacteria.

(b)[3]

One way that a bacterium can be resistant to an antibiotic, such as a β‑lactam, is by possessing protein pumps in its cell surface membrane that remove the antibiotic from the bacterium. The gene for such an efflux pump is located on a plasmid. Outline how the bacterium makes an efflux pump from a gene on a plasmid.

(c(i))[4]

Using Table 2.1, suggest why the MICs of mutant strains 1 and 2 are different from that of strain R.\n\nmutant strain 1\n\nmutant strain 2

(c(ii))[4]

Suggest how a population of strain R of $P.\ aeruginosa$ could be replaced by mutant strain 2.

(ii)[4]

Explain how mutant S could replace a population of strain R of $P.\ aeruginosa$.

Worked solution & mark scheme

This 19-mark question has a full step-by-step worked solution and mark scheme. One marking point: Penicillin inhibits the enzyme / peptidase

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