Biology 9700 · AS & A Level · Fluid mosaic membranes

Fluid mosaic membranes — practice question

Muscle cells possess receptors on their cell surface for the neurotransmitter ACh. These receptors enable the muscle to respond to a nerve impulse. In myasthenia gravis, helper T cells cause a clone of B cells to differentiate into plasma cells and release antibodies that attach to and obstruct these ACh receptors. As a result, the muscles fail to be stimulated and start to deteriorate. A short-term treatment for myasthenia gravis is to inject monoclonal antibodies into the blood. What is the target of these monoclonal antibodies?

  • Aantibodies that bind to ACh receptors
  • Bmuscle cell surface ACh receptors
  • Cplasma cells secreting anti-ACh receptor antibodies
  • Dthe stimulating neurotransmitter ACh

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