Biology 9700 · AS & A Level · Factors that affect enzyme action

Factors that affect enzyme action — practice question

The malarial parasite, Plasmodium, enters red blood cells and degrades haemoglobin. Unbound haem groups are poisonous to Plasmodium, so the parasite changes them into non-toxic, crystalline haemozoin by means of an enzyme, HDP, that occurs in every species of Plasmodium. What would be the long term effect of treating patients with malaria with a drug that inhibits HDP?

  • Aa decreased concentration of free haem groups in infected red blood cells
  • Ba decreased concentration of haemoglobin in infected red blood cells
  • Cmore rapid reproduction of some species of Plasmodium in infected red blood cells
  • Dslower reproduction of all species of Plasmodium in infected red blood cells

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