Biology 9700 · AS & A Level · Control and coordination in mammals

Control and coordination in mammals — practice question

Follicle stimulating hormone (FSH) and luteinising hormone (LH) are each made of two polypeptide chains, the $\alpha$ and $\beta$ chains. The $\alpha$ chains in FSH and LH are the same. The $\beta$ chain in FSH contains 111 amino acids, whereas the LH $\beta$ chain contains 121 amino acids. FSH and LH attach to different receptors in the cell surface membranes of their target cells. This attachment causes steroid synthesis by the target cells.
(a)[3]

Explain why FSH is unable to bind to a LH receptor.

(b(i))[1]

Identify the human female cells that possess FSH receptors.

(b(ii))[1]

Identify the human female cells that possess LH receptors.

(c)[3]

Describe what occurs when FSH binds to its receptors on its target cells.

Worked solution & mark scheme

This 8-mark question has a full step-by-step worked solution and mark scheme. One marking point: Receptor/binding site is not complementary to FSH or not specific to FSH

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