Biology 9700 · AS & A Level · Antibodies and vaccination

Antibodies and vaccination — practice question

Monoclonal antibodies (MAbs) have been used to treat some non-infectious diseases. MAbs can be engineered to attach to a protein on diseased cells, which leads to their destruction by cells of the person’s immune system.
(a(i))[1]

Name the region of an antibody molecule that binds to a protein on diseased cells.

(a(ii))[4]

Suggest how the attachment of monoclonal antibody to the diseased cells leads to their destruction by cells of the person’s immune system.

(b)[1]

Myasthenia gravis is an auto-immune disease. Explain what is meant by auto-immune disease.

Worked solution & mark scheme

This 6-mark question has a full step-by-step worked solution and mark scheme. One marking point: variable region / antigen binding site / $V_H$ and $V_L$

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