Biology 9700 · AS & A Level · Antibodies and vaccination

Antibodies and vaccination — practice question

Antibody molecules are proteins that exhibit primary structure, secondary structure, tertiary structure and quaternary structure. Fig. 1.1 presents a ribbon diagram of an antibody molecule.
(a)[3]

Describe how Fig. 1.1 illustrates both the secondary structure and the tertiary structure of the antibody molecule.

(b(i))[2]

State the functions of the structures labelled X and Y in the production of antibody molecules in the hybridoma cell.

(b(ii))[3]

Outline the stage during which hybridoma cells are formed.

(b(iii))[3]

Outline how monoclonal antibodies are used in the treatment of disease.

(ii)[3]

The hybridoma method used to produce monoclonal antibodies has several stages. One stage is the formation of hybridoma cells. Outline the stage in which hybridoma cells are formed.

(iii)[3]

Outline how monoclonal antibodies are used to treat disease.

Worked solution & mark scheme

This 17-mark question has a full step-by-step worked solution and mark scheme. One marking point: Secondary structure, for example an $\alpha$-helix or $\beta$-pleated sheets

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