Biology 9700 · AS & A Level · Antibiotics

Antibiotics — practice question

Fig. 2.1 shows, as a transmission electron micrograph, the bacterial pathogen responsible for tuberculosis (TB).
(a(i))[1]

Name the pathogen in Fig. 2.1 that causes TB.

(a(ii))[1]

Complete Table 2.1 by putting a tick ($\checkmark$) to show the type of immunity that develops in a person who has received the BCG vaccination.

(b(i))[3]

Rifampicin blocks RNA polymerase in bacterial cells by attaching to a site other than the active site. As a result, polypeptide synthesis is stopped. Suggest and explain how rifampicin prevents polypeptide synthesis in bacterial cells.

(b(ii))[2]

Describe the pattern shown by the data in Fig. 2.2.

(b(iii))[4]

Explain how resistance to drugs such as rifampicin develops.

(ii)[2]

Describe the pattern shown by the data in Fig. 2.2.

(iii)[4]

Explain how resistance to drugs such as rifampicin develops.

Worked solution & mark scheme

This 17-mark question has a full step-by-step worked solution and mark scheme. One marking point: Either $\textit{Mycobacterium tuberculosis}$ or $\textit{Mycobacterium bovis}$

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